{"id":524,"date":"2018-12-05T15:27:05","date_gmt":"2018-12-05T06:27:05","guid":{"rendered":"http:\/\/mathematicians.korea.ac.kr\/sk23\/?p=524"},"modified":"2018-12-05T15:41:02","modified_gmt":"2018-12-05T06:41:02","slug":"%ec%a0%95%ea%b8%b0%ed%8a%b9%ea%b0%95-%ec%83%9d%eb%ac%bc%ec%88%98%ed%95%99","status":"publish","type":"post","link":"https:\/\/mathematicians.korea.ac.kr\/sk23\/2018\/12\/05\/%ec%a0%95%ea%b8%b0%ed%8a%b9%ea%b0%95-%ec%83%9d%eb%ac%bc%ec%88%98%ed%95%99\/","title":{"rendered":"[\uc815\uae30\ud2b9\uac15] \uc0dd\ubb3c\uc218\ud559"},"content":{"rendered":"<p>\uc218\ud559\uacfc 2018\ub144 2\ud559\uae30 \uc815\uae30\ud2b9\uac15\uc785\ub2c8\ub2e4<\/p>\n<p>1. \uc77c\uc2dc : 2018\ub144 12\uc6d4 7\uc77c (\uae08) \uc624\ud6c4 4\uc2dc 30\ubd84 ~ 5\uc2dc 30\ubd84<br \/>\n2. \uc7a5\uc18c : \uc544\uc0b0\uc774\ud559\uad00 526\ud638<br \/>\n3. \uc5f0\uc0ac : \uae40\uc7ac\uacbd (\uce74\uc774\uc2a4\ud2b8)<br \/>\n4. \uc81c\ubaa9 : Mathematics to solve biological puzzles: simplification of deterministic and stochastic systems<br \/>\n5. \ucd08\ub85d : In biological systems, many species interact with multiple timescales.  Because analysis and simulations of such multi-scale systems are challenging, various strategies to simplify the system has been developed. In this talk, I will describe a way to simplify deterministic and stochastic systems by projecting them to lower dimensional slow-manifold. I will also illustrate how we used such approach to solve two biological puzzles: 1) accurate prediction of drug clearance in human liver and 2) molecular mechanisms for robust circadian rhythms against molecular noise.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\uc218\ud559\uacfc 2018\ub144 2\ud559\uae30 \uc815\uae30\ud2b9\uac15\uc785\ub2c8\ub2e4 1. \uc77c\uc2dc : 2018\ub144 12\uc6d4 7\uc77c (\uae08) \uc624\ud6c4 4\uc2dc 30\ubd84 ~ 5\uc2dc 30\ubd84 2. \uc7a5\uc18c : \uc544\uc0b0\uc774\ud559\uad00 526\ud638 3. \uc5f0\uc0ac : \uae40\uc7ac\uacbd (\uce74\uc774\uc2a4\ud2b8) 4. \uc81c\ubaa9 : Mathematics to solve biological puzzles: simplification of deterministic and stochastic systems 5. \ucd08\ub85d : In biological systems, many species interact with multiple timescales. Because analysis &#8230; <a title=\"[\uc815\uae30\ud2b9\uac15] \uc0dd\ubb3c\uc218\ud559\" class=\"read-more\" href=\"https:\/\/mathematicians.korea.ac.kr\/sk23\/2018\/12\/05\/%ec%a0%95%ea%b8%b0%ed%8a%b9%ea%b0%95-%ec%83%9d%eb%ac%bc%ec%88%98%ed%95%99\/\" aria-label=\"[\uc815\uae30\ud2b9\uac15] \uc0dd\ubb3c\uc218\ud559\uc5d0 \ub300\ud574 \ub354 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694\">\ub354 \uc77d\uae30<\/a><\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-524","post","type-post","status-publish","format-standard","hentry","category-news-events"],"distributor_meta":false,"distributor_terms":false,"distributor_media":false,"distributor_original_site_name":"","distributor_original_site_url":"https:\/\/mathematicians.korea.ac.kr\/sk23","push-errors":false,"_links":{"self":[{"href":"https:\/\/mathematicians.korea.ac.kr\/sk23\/wp-json\/wp\/v2\/posts\/524","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mathematicians.korea.ac.kr\/sk23\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mathematicians.korea.ac.kr\/sk23\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mathematicians.korea.ac.kr\/sk23\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/mathematicians.korea.ac.kr\/sk23\/wp-json\/wp\/v2\/comments?post=524"}],"version-history":[{"count":1,"href":"https:\/\/mathematicians.korea.ac.kr\/sk23\/wp-json\/wp\/v2\/posts\/524\/revisions"}],"predecessor-version":[{"id":525,"href":"https:\/\/mathematicians.korea.ac.kr\/sk23\/wp-json\/wp\/v2\/posts\/524\/revisions\/525"}],"wp:attachment":[{"href":"https:\/\/mathematicians.korea.ac.kr\/sk23\/wp-json\/wp\/v2\/media?parent=524"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mathematicians.korea.ac.kr\/sk23\/wp-json\/wp\/v2\/categories?post=524"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mathematicians.korea.ac.kr\/sk23\/wp-json\/wp\/v2\/tags?post=524"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}